Symptoms of GERD (PPI's don't stop reflux... only reduce the acid)

In chronic GERD, regurgitation occurs regularly, spilling acid, bile, and other stomach contents not only into the esophagus but also into the lungs, mouth, pharynx and/or nose. Thus, GERD can lead to a variety of complications including esophagitis, anemia, peptic stenosis, Barrett's esophagus, cough, asthma, recurrent bronchitis, ENT manifestations, sleep disturbance, and in the worst case, even esophageal adenocarcinoma (cancer).

‘Atypical' symptoms associated with GERD can include sore throat, cough, laryngitis, dental erosions, discomfort in the ears and nose, and asthma like symptoms caused by the aspiration of stomach contents into the lungs. These atypical symptoms are typically not resolved through drug treatment alone and require reflux cessation to prevent reoccurrence and progression.

The complications associated with untreated GERD are well documented and can have a significant impact on the quality of life and, in extreme cases, life expectancy. During the early stages of GERD, patients often feel a burning sensation in their chest typically referred to as heartburn. As the disease progresses, the normal anatomy of the GEJ can change reducing the capacity of the ARB to prevent acid from refluxing into the esophagus. When the caustic gastric contents enter the esophagus they damage the esophageal tissue and causes inflammation known as esophagitis. Esophagitis can quickly become a chronic condition and, if the damage is severe, esophageal ulcers can form.