Esophageal Cancer

Barrett’s esophagus is a condition in which the tissue lining the esophagus—the muscular tube that connects the mouth to the stomach—is replaced by tissue that is similar to the lining of the intestine. This process is called intestinal metaplasia.

No signs or symptoms are associated with Barrett’s esophagus, but it is commonly found in people with gastroesophageal reflux disease (GERD). A small number of people with Barrett’s esophagus develop a rare but often deadly type of cancer of the esophagus.

Barrett’s esophagus affects about 1 percent of adults in the United States. The average age at diagnosis is 50, but determining when the problem started is usually difficult. Men develop Barrett’s esophagus twice as often as women, and Caucasian men are affected more frequently than men of other races. Barrett’s esophagus is uncommon in children.

http://digestive.niddk.nih.gov/ddiseases/pubs/barretts/

Asthma and GERD Linked

July 25, 2008 -- Chronic heartburn may alter the immune system and raise the risk of asthma, according to a new study that helps explain why so many people with asthma also suffer from gastroesophageal reflux disease (GERD).

Researchers say the link between asthma and GERD has been a mystery for years. Previous studies have shown that 50%-90% of people with asthma also suffer from gastric reflux, but until now the relationship between the two conditions was unclear.

The study shows that inhaling small amounts of stomach acid back up into the esophagus and lungs, a hallmark of GERD, slowly produces changes in the immune system that may lead to the development of asthma.

http://www.webmd.com/asthma/news/20080725/link-found-between-asthma-and-gerd